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系统性红斑狼疮患者外周血抗内皮细胞抗体的检测 被引量：5

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摘要 目的探讨系统性红斑狼疮(SLE)患者外周血IgG型抗内皮细胞抗体(IgG-AECA)的检测及意义。方法采用间接免疫荧光法检测25例活动期SLE患者、27例缓解期SLE患者及25例健康志愿者外周血IgG-AECA及其滴度。结果 IgG-AE-CA阳性率在SLE活动期组、SLE缓解期组、健康对照组分别为56.00%、22.22%及0,两两比较差异有统计学意义(P<0.05),SLE活动期组IgG-AECA滴度与SLEDAI评分呈正相关。结论 IgG-AECA滴度与SLE病情活跃有一定相关性,可尝试作为判断疗效及SLE病情活动的临床观察指标。
作者 周培媚 路永红 程晓云 朱颜俊 陈前明 树瑜 苏怡帆 熊霞
机构地区 成都市第二人民医院皮肤科 成都市第二人民医院风湿免疫科 泸州医学院附属医院皮肤科
出处 《重庆医学》 CAS CSCD 北大核心 2010年第22期3104-3105,共2页 Chongqing medicine
基金 四川省卫生厅科研课题资助项目(2007[070380])
关键词 红斑狼疮 系统性 抗内皮细胞抗体 狼疮活动性
分类号 R593.241 [医药卫生—内科学] R446.62 [医药卫生—诊断学]
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参考文献7

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二级参考文献10

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共引文献2

同被引文献58

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二级引证文献25

重庆医学
2010年 第22期

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