摘要
目的 了解山西省太原市5岁以下腹泻住院儿童四种主要腹泻病毒的流行情况.方法 收集山西儿童医院2007年10月至2008年11月5岁以下全部住院腹泻患儿的粪便标本,采用ELISA试剂盒来检测轮状病毒;采用聚合酶链反应（PCR）检测腺病毒;逆转录-聚合酶链反应（RT-PCR）法检测星状病毒和杯状病毒并对轮状病毒进行分型.结果 346份标本中轮状病毒占40.8%、杯状病毒占7.5%、星状病毒占6.4%、腺病毒占3.2%.对141份轮状病毒阳性标本进行G1P分型,G1型是最优势株,P型优势株为P[8].四种病毒主要是感染2岁以下婴幼儿,RV有明显的季节的特征,9-11月份（48.92%）为发病高峰.结论 轮状病毒为最主要的病毒病原,G1P[8]型为主要流行株,秋冬季为发病高峰,2岁以下为发病高危人群,混合感染多见.
Objective To study the epidemiologic characteristics of virus-induced acute diarrhea in children under 5 years old in Taiyuan, Shauxi province. Methods Stool specimens and clinical data were collected from 346 inpatients with acute diarrhea from children less than 5 years old. Rotavirus-positive specimens were identified by ELASA kit. Calicivirus and astrovirus were detected by reverse transcription-polymerase chain reaction （RT-PCR）;Adenovirus was done by polymerase chain reaction（PCR）. Results Of the 346 specimens, the percentage of samples with Rotavirus, Calicivirus, Astrovirus, and Adenovirus was 40.8%,7.5% , 6.4% and 3.2%. Among 141 rotavirus positive samples, serotype G1 （42.6%）was the predominant strain. More than 95% of viral diarrhea patients under hospitalization occurred among children younger than 2 years. Conclusion Rotavirus is the major pathogen contributing to the acute diarrhea. The disease is generally peaks at autumn/winter. The predominant rotavirus strain circulated was G1P[8].
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
北大核心
2010年第1期8-10,共3页
Chinese Journal of Experimental and Clinical Virology
关键词
轮状病毒属
腹泻
儿童
住院
流行病学
Rotavirus
Diarrhea
Child, hospitalized
Epidemiology
