摘要
目的探讨杭州市5岁以下腹泻患儿病毒性腹泻病原分布以及主要病原流行病学特点,为病毒性腹泻的防控提供参考依据。方法采集2014年9月-2015年8月杭州市儿童医院5岁以下腹泻患儿的大便标本共3 190份,用免疫荧光法检测A群轮状病毒、40.41型肠道腺病毒、星状病毒血清型I和诺如病毒,并进行分布情况分析。结果 3 190例标本中A群轮状病毒阳性率为29.56%(943/3 190),40.41型肠道腺病毒阳性率为2.32%(74/3 190),星状病毒血清型I和诺如病毒阳性率为0.13%(4/3 190),其中12月份A群轮状病毒阳性率最高,不同性别病毒病原体分布差异无统计学意义(P>0.05),但A群轮状病毒不同年龄段病原体分布差异有统计学意义(P<0.01)。结论 A群轮状病毒是杭州市婴幼儿秋、冬季腹泻最主要致病原,40.41型肠道腺病毒感染居第二,有混合性病毒感染发生,3岁以下儿童是重点防控人群。
Objective To explore the pathogen distribution and etiologic characteristics of infantile viral diarrhea under 5 years old in Hangzhou,so as to provide reference for the prevention and control of viral diarrhea. Methods From September,2014 to August,2015,the stool specimens were collected from 3 190 children under 5 years old with acute diarrhea. Group A rotavirus,40. 41 adenovirus,astrovirus and norovirus were detected by immumofluorescence method. And the distribution was analyzed.Results Among 3 190 cases,the positive rate of group A rotavirus angiten was 29. 56%（ 943 /3190）,and that of 40. 41 enteral adenorirus angiten was 2. 32%（ 74 /3 190）,and that of astrovirus and norovirus angiten were 0. 13%（ 4 /3190）,with the highest positive rates of group A rotavirus in December. Difference on pathogen distribution between genders was not statistically significant（ P〉0. 05）,but that of group A rotavirus angiten between different ages was statistically significant（ P〈0. 01）.Conclusion Group A rotavirus is still the major etiologic agents of acute infantile diarrhea in Hangzhou in autumn and winter,followed by 40. 41 enteral adenorirus angiten,and mixed infection still exist. Children under 3 years old is the focus group for the prevention and control of viral diarrhea.
出处
《中国卫生检验杂志》
CAS
2016年第6期877-879,共3页
Chinese Journal of Health Laboratory Technology
