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涎腺腺样囊性癌p53基因蛋白的表达及其临床意义 被引量:1

An experimental study of the effect of occlusal splint on temporomandibular joint intraarticular pressure
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摘要 目的 为探讨涎腺腺样囊性癌p53 基因蛋白的表达及其临床意义。方法 作者应用流式细胞术及细胞免疫荧光染色技术,对涎腺腺样囊性癌p53 基因蛋白的表达进行了定量研究。结果 结果表明,正常涎腺组织p53 表达均为阴性,涎腺腺样囊性癌p53 基因蛋白表达量及表达阳性率与该肿瘤的浸润情况密切相关,p53 基因蛋白表达量与预后亦有相关性。结论 p53 基因蛋白表达量及表达阳性率与腺样囊性癌组织学分型、 D N A Objective To investigate the effect of occlusal splint on temporomandibular joint (TMJ) intraarticular pressure (IAP).Methods Measuring IAP of TMJ upper cavity in three domestic dogs during clenching with and without the splint in situ using polygraph systems,RM-6000.Results TMJ IAP was accordingly 6.4±1.5 Kpa and 0.6±0.2 Kpa without and with the splint in situ,and there was statistically significant differences.Conclusion One of the machenisms of occlusal splint in the treatment of craniomandibular disorders is to reduce the IAP,and thus exerts therapeutic effect on TMJ symptoms.
出处 《现代口腔医学杂志》 CAS CSCD 1999年第2期86-88,共3页 Journal of Modern Stomatology
关键词 涎腺肿瘤 腺样囊性癌 P53基因 DNA Temporomandibular joint Intraarticular pressure Occlusal splint
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