摘要
目的探讨血清HBV病毒载量与血清学标志物和肝功能指标ALT、GGT之间的关系。方法用FQ-PCR法检测乙型肝炎病毒载量、ELISE法检测乙型肝炎血清学标志物及酶法检测肝功能指标ALT、GGT,对222例患者血清标本的上述3种指标结果进行分析。结果在3种常见的血清学模式中,HBsAg、HBeAg和抗-HBc阳性者(135模式)HBVDNA阳性率为77.8%,肝功能中ALT和(或)GGT异常占54.0%;HBsAg、HBeAb和抗-HBc阳性者(145模式)HBVDNA阳性率为43.2%,肝功能中ALT和(或)GGT异常占48.4%;HBsAg、抗-HBc阳性者(15模式)HBVDNA阳性率为48.4%,肝功能中ALT和(或)GGT异常占45.3%。结论 HBV病毒载量与乙型肝炎血清学标志物之间具有相关性,肝功能指标ALT、GGT与乙型肝炎血清学标志物之间差异无统计学意义,HBV病毒载量与肝功能指标ALT、GGT具有一定的相关性。
Objective Discussion blood serum HBV virus load capacity and serology markers and between hepatic functionality target ALT,GGT relations. Methods Determines the virus load capacity with the FQ-PCR,ELSIA method determination hepatitis B serology designated object and enzyme method determination hepatic functionality target ALT,GGT, carries on the analysis to 222 example hepatitis B patient blood serum specimen＇s above three kind of target result. Results In three kind of common serology patterns, HBsAg. HBeAg and the anti-HBc masculine gender （135 patterns）the HBV-DNA masculine gender rate is 77.8% ,In the hepatic functionality ALT and （or）GGT exceptionally accounts for 54.0% ; HBsAg. HBeAb and the anti HBc masculine gender （145 patterns）the H13V-DNA masculine gender rate is 43.2% ,ln the liver function ALT and（or）GGT exceptionally accounts for 48.4% ;In the hepatic functionality ALT and（or）GGT exceptionally accounts for 45.3% . Conclusion The HBV virus load capacity and between the hepatitis B serology designated object has the relevance ,hepatic functionality target ALT,GGT and between hepatitis B serology designated object difference non-statistics significance,The HBV virus load capacity and hepatic functionality target ALT,GGT have certain relevance.
出处
《国际检验医学杂志》
CAS
2010年第10期1083-1084,共2页
International Journal of Laboratory Medicine
