摘要
目的介绍听觉诱发电位整组波形资料的平均组合曲线绘制方法并进行数据分析。方法将5只南美栗鼠暴露于窄带噪声2h。在噪声暴露前及暴露后1h分别测试动物的听性脑干反应和耳蜗听神经复合动作电位。将每只南美栗鼠的听性脑干反应图形数据和听神经复合动作电位图形数据进行组合后分别绘制成该组动物暴露噪声前和暴露噪声后的平均听觉诱发电位图形,并对暴露噪声前后听觉诱发电位阈值、振幅和潜伏期进行比较和分析。结果整组波形资料的平均听觉诱发电位图形比单只动物的听觉诱发电位图形更能如实反映该组动物整体听觉诱发电位的实际水平。噪声引起的暂时性阈移伴随着听觉诱发电位振幅的降低,但并不延长听觉诱发电位的潜伏期和听觉信号沿着听觉通路的中枢传导时间。结论听觉诱发电位的平均波形图接近于该组动物的实际平均听觉反应阈值,可以客观反映整组动物的平均听觉水平。噪声引起的暂时性阈移仅影响耳蜗内听觉信号的产生而并不影响听觉信号沿着听觉神经通路的传递速度。
Objective To introduce a combinatorial graphics mode to show the averaged auditory evoked potentials and data analysis. Methods Five chinchillas were exposed to a narrowband noise for 2 hours. Both the auditory brainstem response （ABR） and the cochlear compound action potential （CAP） were tested before test and 1 hour after noise exposure. Both the averaged ABR waveform and CAP waveform were constructed from individuals in the group before test and after noise exposure respectively. The threshold, amplitude, and the latency of auditory evoked potentials was compared and analyzed. Results The averaged waveforms of auditory evoked potentials were more true to nature to reflect the real hearing level in the whole group than a selected single waveform from any individual. Noise-induced tem- porary threshold shifts in auditory evoked potentials were associated with a significant decrease in amplitude, but do not affect the latency and the conductibility of hearing signals. Conclusions The threshold in the averaged ABR and CAP waveforms is close to the real average threshold in the group that can be used to reflect the hearing function in the whole group with objectivity. The noise exposure in the current study only affect the generation of hearing signals in the coehlea, but does not delay the signal transportation along the auditory pathway. （Chin J Ophthalmol and Otorhinolaryngol,2010, 10 ： 280-284 ）
出处
《中国眼耳鼻喉科杂志》
2010年第5期280-284,共5页
Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词
听觉诱发电位
图形方式
噪声
南美栗鼠
Auditory evoked potential
Graphics mode
Noise
Chinchilla
