摘要
β羧乙基锗倍半氧化物（Ｇｅ１３２）及其衍生物是一大类具有调节机体免疫和维持体内代谢平衡的单有机锗化合物〔１〕．为改善其亲油亲水匹配性能，提高其抗癌药效，设计合成了一类新型双有机取代锗氢氧化物〔２〕．本文报道了其中的双（β羧乙基）锗氢氧化物（简称...
A simple and efficient synthetic method of the title compound has been
advanced.The structure and chemphysical properties were characterized.The activity of cleaning
superoxy anion and hydroxy radical is lower than that of Ge132.But the activity of inhibition
mitosis of the QGY cells of the human liver cancer is obviously higher than that of Ge132.
出处
《中国药物化学杂志》
CAS
CSCD
1999年第2期127-129,共3页
Chinese Journal of Medicinal Chemistry
关键词
羧乙基
双锗氢氧化物
合成
生物活性
di(carboxylethyl)germanium dihydroxide
synthesis
bioactivity
