摘要
目的探讨应用小剂量阿托品治疗急性有机磷农药中毒的临床疗效。方法该研究对我院2006年3月至2010年2月确诊的急性重度有机磷农药中毒患者病历资料进行回顾性分析，对照组为进行常规治疗的确诊患者，治疗组为应用小剂量阿托品进行治疗的确诊患者。对二组患者治疗结果进行临床分析。二组间均数比较采用方差分析。计数资料采用四格表x2检验。结果该研究入选患者207例，二组患者年龄、性别及服药剂量分布差异无统计学意义（P〉0.05）。治疗组存活率较对照组明显提高，住院时间明显缩短，发生呼吸衰竭等并发症较对照组明显减少。结论小剂量阿托品治疗急性重度有机磷农药中毒疗效明显优于传统剂量阿托品治疗。
Objective To investigate the effect of atropine in the treatment of acute organopbosphorus pesticide poisoning. Methods The data of severe acute organophosphorus pesticide poisoning cases from March 2006 to February 2010 in our Emergency Department were retrospective reviewed. The eases were divided into treatment group and control groups. Control group included cases that received conventional therapy, treatment group included cases that received therapy with low dose atropine. Mean of two groups were analyzed by using ANOVA, and the rate were compared with chi-square test. Statistical significance was established at a P value of less than 0. 05. Results 207 cases were included in our study. There was no significant difference in age, gen- ders and poisoning dose between the two groups （P 〉 0.05 ）. The survival rate in the treatment group was higher than that in control group. The length of stay was shorter, and the complications such as respiratory failure was fewer. Conclusion Low dose atropine is better than conventional dose atropine in treatment of severe acute organophosphorus pesticide poisoning.
出处
《中国临床实用医学》
2010年第10期68-69,共2页
China Clinical Practical Medicine
关键词
有机磷农药中毒
小剂量
阿托品
临床疗效
Acute organophosphorus pesticide poisoning
Low dose
Atropine
Therapeutic effect
