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农药中毒诊治中42例阿托品中毒致呼吸肌麻痹的分析 被引量:44

Analysis of the respiratory muscle paralysis induced by atropine overdosages in the treatment of pesticide poisoning
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摘要 目的 研究不同农药中毒治疗中因阿托品中毒所致的呼吸肌麻痹 (RMP)发生率 ,探讨阿托品治疗与RMP的关系 ,并对阿托品中毒的原因进行分析。方法 对 4 2例不同组别农药中毒病人进行分类分析 ,比较不同组别中阿托品治疗导致RMP的发生率及阿托品用量间的关系。结果 阿托品在治疗有机磷酸酯类、氨基甲酸酯类、混配农药类、除虫菊酯类后导致的RMP的发生率依次为 6 0 %、16 .5 %、16 .5 %、7.1%。阿托品在治疗非有机磷中毒和有机磷中毒病人中用量分别为 80~32 0mg和 2 90~ 6 2 5 0mg。结论 农药中毒治疗时 ,阿托品用量一定要根据毒物类别、中毒途径及中毒程度而定 ,短时内盲目大剂量滥用阿托品可导致RMP。 Objective To investigate the incidence of respiratory muscle paralysis(RMP) induced by atropine overdosage during the treatment of the pesticide poisoning and explore the relationship between atropine overdosage and RMP,analyse the cause of the poisoning. Methods We analysed 42 patients in different groups, and compared the relationship between the incidence of RMP and the atropine dosage in different groups.Results The incidence of the RMP using atropine in the treatment of poisoning such as organic phosphate ,carbamates,mixture pesticide and pyrethrin was 60%,16.5%,16.5%,7.1% in turn.The atropine dosage was 80~320 mg and 290~6 250 mg in the treatment of non-organophosphate poisoning and organophosphate poisoning.Conclusion During the poisoning treatment ,the dosage of atropine should be used according to the type of the poisoning,the way of the poisoning and degree of the poisoning.The atropine overdosage in short terms could cause RMP.
出处 《中国急救医学》 CAS CSCD 北大核心 2005年第3期183-185,共3页 Chinese Journal of Critical Care Medicine
关键词 农药中毒 阿托品中毒 呼吸肌麻痹 分析 Pesticide poisoning Atropine overdosage Respiratory muscle paralysis Analysis
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