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埃索美拉唑镁联合盐酸依托必利分散片治疗反流性食管炎40例 被引量:10

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摘要 目的评价埃索美拉唑镁联合盐酸依托必利分散片治疗反流性食管炎的疗效。方法对确诊的78例反流性食管炎患者随机分为两组。治疗组40例,每天晨服埃索美拉唑镁肠溶片20 mg,盐酸依托必利分散片每次50 mg,tid,饭前15~30 min口服;对照组38例,每天晨服雷贝拉唑钠10 mg,盐酸依托必利分散片每次50 mg,tid,饭前15~30 min口服,两组疗程均为8周。结果治疗组临床有效率97.5%,对照组为73.7%,两组差异有显著性(P〈0.05),胃镜下疗效复查有效率治疗组为87.5%,对照组为52.6%,两组比较差异有显著性(P〈0.05)。结论埃索美拉唑镁联合盐酸依托必利分散片治疗反流性食管炎疗效安全可靠。
作者 王健苗
出处 《医药导报》 CAS 2010年第10期1311-1313,共3页 Herald of Medicine
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  • 1金伟森,李金锁,杨绍勃,金虎.慢性功能性便秘对老年人健康的影响及防治[J].武警医学,2004,15(7):506-509. 被引量:7
  • 2郝云龙,毛兆明,范例.埃索美拉唑联合莫沙必利治疗反流性食管炎疗效观察[J].武警医学,2005,16(4):259-261. 被引量:14
  • 3Adachi K, Hashimoto T, Hamamoto N, et al. Symptom relief in patientswith reflux esophagitis: Comparative study of omep razole, lansop razole,and rabep razole[J]. Gastroenterol Hepatol, 2003, 18: 1392-1398.
  • 4Gob KL. "On-demand" therapy for gastroesophageal reflux disease: Are current proton pump inhibitors good candidates [J]. GastroenterolHepatol, 2006,21 (Suppl 5) : S115-S118.
  • 5Cheung TK, Wong BC. Proton- pump inhibitor failure/resist ance:Proposed mechanisms and therapeutic algorithm [J]. Gastroenterol Hepatol, 2006,21 (Suppl 5) :S119-S124.
  • 6Labenz J, Naucler E, Eklund SA comparison of esomeprazole 40rag once daily and pantoprazole 40mg once daily for thehealing of reflux esophagitis[J]. Gut, 2003,52 : 241.
  • 7[1]Per-ove S, Martha F, Jakobina, et al. Assessment of gastric emptying :Comparison of solid scintigraphic emptying and emptying of radiopaque markers in patients and healthy subjects. Dig Dis Sci, 1999; 44:729~734.
  • 8[2]Yuji I, Naoshi S, Ken-ichi K, et al. Stimulatory effect of HSR-803 on ileal motor activity. Jan J Pharmacol, 1993;62:395~401.
  • 9[3]Yuji I, Naoshi M, Fujie M,et al. Stimulatory effect of HSR-803 on normal and delayed gastrointestinal propulsion. Jan J Pharmacol, 1991;56: 261~269.
  • 10[4]Jebbink HJA, vanBerge-Henegouwen GP, Akkermans LMA. Small intestinal motor abnormalities in patients with functional dyspepsia demonstrated by ambulatory manometry. Gut, 1996; 38: 694~700.

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