摘要
目的：研究１５例急性心肌梗塞患者外周血淋巴细胞亚群和活性标志的变化。方法：流式细胞仪技术。结果：急性心肌梗塞患者外周血淋巴细胞ＣＤ＋３ＤＲ＋和ＣＤ＋４ＤＲ＋百分率明显高于对照组，ＣＤ＋８ＤＲ＋无明显变化，ＣＤ＋４ＤＲ＋／ＣＤ＋８ＤＲ＋比值显著增高；ＣＤ＋４ＤＲ＋细胞占相应亚群的百分率显著增高。结论：急性心肌梗塞患者存在免疫功能紊乱，辅助性Ｔ淋巴细胞处于高活性状态。
AIM: The peripheral blood T-lymphocytes subsets and its active markers in patients with acute myocardial infarction were studied.METHODS:Low cytometric analysis.RESULTS:The percentages of CD + 3DR + and CD + 4DR + T-lymphocytes and the ratio of CD + 4DR +/CD + 8DR + were significantly increased in patients with acute myocardial infarction. Where CD + 8DR + T-lymphocytes had no marked difference between normal controls and patients with acute myocardial infarction.CONCLUSION:The disturbance of activated T-lymphocyte subsets and the highly state of activated T-helper lymphocyte were found in patients with acute myocardial infarction.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1999年第5期433-435,共3页
Chinese Journal of Pathophysiology
关键词
心肌梗塞
HLA-DR抗原
T细胞亚群
Myocardial infarction
Lymphocyte transformation
HLA-DR antigens
