摘要
目的观察中药心复平治疗心阳不振型冠心病合并室性早搏的临床疗效及安全性。方法将90例心阳不振型冠心病合并室性早搏患者随机分为3组,每组30例。治疗组服用心复平,中药对照组服用稳心颗粒,西药对照组服用可达龙。连续用药4周,观察临床疗效,治疗前后24小时动态心电图及中医症状的变化情况。结果室性早搏总有效率治疗组为76.7%,西药对照组为90.0%,中药对照组为60.0%,治疗组低于西药对照组,无显著性差异(P>0.05),但高于中药对照组(P<0.05);中医证候有效率治疗组为83.3%,西药对照组为76.7%,中药对照组为66.7%,治疗组高于中药对照组(P<0.05)。3组均未见严重不良反应。结论中药心复平治疗冠心病合并室性早搏疗效确切,安全性高。
Objective To observe the efficacy and safety of ＂Xinfuping Decoction＂ in the treatment of coronary, heart disease with ventricalar premature beats of heart- yang inactivation. Methods Ninety subjects were randomized into three groups ： group A in which 30 cases were treated with ＂Xinfuping Decoction＂, group B in which 30 eases were treated with ＂Wenxin Granule＂ and group C in which 30 cases were treated with amiodarone, all with a course of 4 weeks. The clinical effica- cy, 24-hour electrocardiogram by Halter, symptoms and adverse effects were observed. Results The total effective rate for ventrieular premature beats was 76.7% in group A, 60.0% in group B and 90.0% in group C, with a significant difference between groups A and C （ P 〈0.05 ） ; the total effective rate for symptoms was 83.3% in group A, 66.7% in group B and 76.7% in group C, with a significant difference between groups A and B（P 〈0.05）. There were no serious side effects were found in the three groups. Conclusion ＂Xinfuping Decoction＂ is effective and safe for coronary heart disease with ventricular premature, beats.
出处
《上海中医药杂志》
2010年第9期34-36,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市卫生局中医药科研基金课题(2006L016A)
关键词
冠心病
室性早搏
心阳不振
心复平
Coronary heart disease
ventricular premature beats
heart-yang inactivation
＂Xinfuping Decoction＂
