摘要
[目的]研究川续断(Dipsacus asperoides)的化学成分。[方法]采用溶剂提取、重结晶和硅胶色谱方法分离纯化,根据氢谱、碳谱以及与对照品共薄层色谱鉴定化合物的结构。[结果]从川续断的70%乙醇提取物中分离鉴定了10个化合物:β-谷甾醇(1),蔗糖(2),胡萝卜苷(3),乙二醇(4),3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元(5),3-O-α-L-吡喃阿拉伯糖-齐墩果酸-28-O-β-D-吡喃葡萄糖-(1→6)-β-D-吡喃葡萄糖苷(6),木通皂苷D(7),3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元-28-O-β-D-吡喃葡萄糖苷(8),马钱子苷(9),TriplostosideA(10)。[结论]化合物(4)为首次在川续断属植物中分离得到。
[Objection]To study the chemical constituents in Dipsacus asperoides.[Methods]The compounds were separated and purified by solvent extraction,recrystallization and chromatography on silica gel and polyamide column.Their structures were elucidated on the basis of 1H-NMR,13C-NMR, and co-TLC with authentic samples.[Results]Ten compounds were identified：β-sitosterol（1）,Sucrose （2）,Daucosterol（3）,Ethylene glycol（4）,Cauloside A（5）,3-O-α-L-arabinopyranosyl-Oleanolicacid-28-β-D-glucopyranosyl-（1→6）-β-D-glucopyranoside（6）,Akebiasaponin D（7）,HN saponin F（8）,Loganin （9）,Triplostoside A（10）.[Conclusion]Compound 4 was obtained from the title plant for the first time.
出处
《天津中医药大学学报》
CAS
2010年第3期147-150,共4页
Journal of Tianjin University of Traditional Chinese Medicine
基金
科技部国际合作项目(2008DFB30070)
天津市重点项目(06TXTJJCB600)
关键词
川续断
三萜皂苷
常春藤皂苷元
Dipsacus asperoides
triterpenoid saponin
hederagenin
