摘要
应用简易形态学法及化学发光法检测了几种疾病病人的红细胞增强中性粒细胞(PMN)吞噬作用的功能及过氧化物岐化酶(SOD)的活性。结果发现恶性肿瘤病人的红细胞这一功能明显低下。自身免疫病、感染等也明显降低,但与恶性肿瘤病人间差异有显著意义。肿瘤患者间差异无显著意义。红细胞内SOD变化与其一致。经治疗后,肿瘸病人红细胞的此项功能有明显回升。提示检测红细胞促吞噬功能这一指标对区别良恶性疾病及判定疗效均有一定价值。
Using a simple morphologic method and a chemical luminescent method, the function of erythrocyte enhancing neutrophil phagocytosis and the activity of SOD were determined. It was found that the function of RBC from patients with malignant tumor or leukemia was much weaker than that of healthy subjects and lower than that of infectious or autoimmune disease patients. The variation in SOD activity was comparable. The RBC enhancing effect to phagocytosis tended to recover after effective treatment. These results indicate that the assay of RBC function in enhancing phagocytosis might be used to help differentiating malignant from benign diseases and to judge curative effect.
出处
《上海医学》
CAS
CSCD
北大核心
1990年第6期346-348,共3页
Shanghai Medical Journal
