摘要
目的对健康产妇和非麻疹婴幼儿的麻疹IgG水平进行评估,以了解其对麻疹病毒的抵抗能力。方法收集复旦大学附属妇产科医院健康产妇静脉血100份、新生儿(与产妇非配对,非麻疹患儿)血液52份、2～6月龄婴儿(非麻疹患儿)静脉血52份分别进行麻疹病毒抗体IgG检测。结果受检的100例健康产妇中47例(占47%)达到保护性抗体水平,仅9例(占9.0%)麻疹抗体滴度可以在抵抗麻疹病毒侵袭的过程中起到比较明确的作用;受检的52例新生儿以及52例2～6月龄婴儿中分别有20例(占38.46%)和6例(占11.54%)达到保护性抗体水平,仅新生儿中5例(占9.61%)麻疹抗体滴度可以在抵抗麻疹病毒侵袭的过程中起到比较明确的作用。结论上述人群麻疹保护性抗体水平均较低,产妇、新生儿麻疹抗体水平存在一定的相关性,2～6月龄婴儿麻疹抗体水平低于产妇以及新生儿。
Objective Evaluate the level of measles＇ IgG in heahhy lying-in mothers and non-measles infants to assess their protective competence to measles. Methods We collected blood samples from 100 healthy lying-in mothers, 52 non-measles newborns and 52 non-measles infants of 2- 6 months old, and Enzyme Linked ImmunoSorbent Assay （ELISA） was applied to detect the levels of MV IgG. Results Totally 47 out of the 100 （47.0%） healthy lying-in mothers had protective competence and only 9 of them （9.0%） had the obvious protective competence. In the 52 newborns and 52 infants of 2- 6 month 20 （38.46%） and 6 （11.54%） cases respectively had protective competence and only 5 of the newborns （9.61% ） had the obvious protective competence to prevent them from being infected by measles virus. Conclusion The levels of measles＇ IgG in these people are low. There is some kind of correlation between lying-in mothers and newborns and the levels in 2 - 6-month old infants are lower.
出处
《中国实用儿科杂志》
CSCD
北大核心
2010年第8期638-641,共4页
Chinese Journal of Practical Pediatrics
基金
上海市公共卫生重点学科建设项目(08GWZ00102)
