摘要
目的:探讨血清CA125、CA199、癌胚抗原(CEA)和甲胎蛋白(AFP)的检测在卵巢肿瘤诊断中的价值。方法:采用化学发光法检测卵巢恶性肿瘤、良性肿瘤患者血清CA125、CA199、CEA及AFP水平。结果:卵巢恶性肿瘤患者血清CA125、CA199水平明显高于卵巢良性肿瘤患者(P<0.01),CEA和AFP值在卵巢恶性肿瘤与卵巢良性肿瘤患者间的差异无统计学意义(P>0.05)。结论:CA125、CA199的检测有助于对卵巢恶性肿瘤诊断,而CEA及AFP的检测对卵巢恶性肿瘤的诊断无明显价值。
OBJECTIVE：To study the diagnostic value of the cancer antigen 125（CA125）,cancer antigen 199（CA199）,CEA and AFP in patients with ovarian tumors.METHODS：RIA was used to measure the levels of serum CA125,CA199,CEA and AFP in patients with benign and malignant ovarian tumors.RESULTS：Serum CA125 and CA199 levels were significantly higher in the patients with malignant ovarian tumor than those with benign ovarian tumor（P〈0.01）,The differences of CEA and AFP levels between benign and malignant ovarian tumors were not significant（P〉0.05）.CONCLUSION：The single detection of CA125 and CA199 may be the best method for diagnosing ovarian tumors,and the detection of AFP and CEA has no value for diagnosing ovarian tumors.
出处
《癌变·畸变·突变》
CAS
CSCD
2010年第4期315-316,共2页
Carcinogenesis,Teratogenesis & Mutagenesis
关键词
卵巢肿瘤
癌抗原125
糖链抗原199
癌胚抗原
甲胎蛋白
ovarian tumors
cancer antigen 125
carbohydrate antigen 199
carcinoembryonic antigen
alpha-fetoprotein.
