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动态血压监测评价苯磺酸左旋氨氯地平联合吲哒帕胺缓释片治疗高血压病疗效观察 被引量:7

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摘要 目的:分析评价苯磺酸左旋氨氯地平联合吲哒帕胺缓释片对高血压患者降压疗效及靶器官的保护作用。方法:将60例高血压患者均每日苯磺酸左旋氨氯地平2.5mg及吲哒帕胺缓释片1.5mg联合口服治疗8周。用药前及服药8周后复查动态血压监测,并记录肌酐清除率、尿微量白蛋白、射血分数、电解质、血尿酸等参数。结果:服药8周后患者收缩压,舒张压明显降低,与治疗前比较差异有显著性(P<0.01);血压变异率和血压负荷,用药后明显降低,服药后血压谷峰比值明显高于用药前;与用药前比较,服药8周后内生肌酐清除率,左室射血分数明显增加,尿微量白蛋白明显减少,无严重的电解质及代谢紊乱。结论:苯磺酸左旋氨氯地平联合吲哒帕胺缓释片对高血压患者有稳定降压和明确靶器官保护效应。
出处 《数理医药学杂志》 2010年第4期487-488,共2页 Journal of Mathematical Medicine
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