摘要
为寻求合理有效的给药时间 ,对 40例高血压患者进行观察 ,随机将其分为两组 :A组 6 :0 0给药 ,B组 8:0 0给药 ,均为长效降压药吲达帕胺 2 .5 mg,口服。 2周后行动态血压监测。结果显示 A组的 2 4h平均压、日间平均压和血压负荷均低于 B组 (P <0 .0 1,P <0 .0 5 ,P <0 .0 5 ) ,提示晨 6 :0 0给药效果优于 8:0 0给药 ,建议长效降压药给药时间以 6 :0
To explore the rational and effective time of administration,40 observed patients with hypertention were randomly divided into 2 groups. Groups A and B were given 2.5 mg of indapamide,a long acting antihypertensive at 6:00 and 8:00 respectively.Ambulatory blood pressure(ABP) monitoring was performed 2 weeks after administration.The results showed that 24 h mean blood pressure,mean blood pressure between days and blood pressure load in group A were lower than those in group B,indicating that administration at 6:00 is better than that at 8:00 .The author suggests that long acting antihypertensives should be administered at 6:00.
出处
《解放军护理杂志》
2001年第3期8-9,共2页
Nursing Journal of Chinese People's Liberation Army
关键词
长效降压药
给药时间
动态血压
平均血压
高血压
long acting
antihypertensives
time of administration
ambulatory blood pressure