摘要
目的研究细胞免疫在尖锐湿疣（ＣＡ）发病机理中的作用及用胸腺肽治疗的效果。方法应用ＡＰＡＡＰ法检测３８例ＣＡ患者外周血Ｔ细胞亚群，并用胸腺肽治疗。结果ＣＡ患者ＣＤ８升高，ＣＤ４、ＣＤ４／ＣＤ８下降。治疗后３个月内未复发的２５例患者，Ｔ细胞恢复正常，而８例复发者，治疗前后Ｔ细胞亚群无明显变化。结论提示患者存在细胞免疫功能缺陷。胸腺肽治疗获得较好效果。
Objective To study the role of celluar immunity in pathogenesis of condyloma acuminata (CA) and the effect of thymus peptide therapy.Methods The T cell subpopulation in peripheral blood of thirty eight adult patients with CA were determined by APAAP.The patients were treated with thymus peptide.Results Decrease of CD 4,CD 4/CD 8 and increase of CD 8 were found in CA group as compared with the controls.In 25 patients,who had no relapse in 3 months after treatment,the T cell recovered to normal.There was no significantl change in 8 patients with relapse in 3 months after treatment.Conclusion These results revealed that cellular immunity was impatired in CA patients and suggested that CA patients treated with thymus peptide could get some better effects.
出处
《中国皮肤性病学杂志》
CAS
北大核心
1999年第2期98-99,共2页
The Chinese Journal of Dermatovenereology
关键词
尖锐湿疣
T细胞亚群
胸腺肽
治疗
Condyloma acuminata T cell subpopulation Thymus peptide
