摘要
目的探讨原发性肝细胞癌患者体内β-葡萄糖醛酸酶（β-G）变化现规律。方法采用ELISA法、免疫组化法对31例原发性肝细胞癌患者血清肤癌组中β-G进行同步研究，并对其中10例进行免疫电镜研究。结果β-G在肝癌患者血清及癌组织中部呈过度表达，与对照组有非常显著性差异（P＜0.01）。结论对β-G机能学及形态学的联合检测，可能成为肝癌诊断的辅助指标。
Objective To study the change of β-glucuronidase (β-G ) in the patients with primary hepatic carcinoma. Method β-G was detected synchronously [both in the serum and carcinoma tissue of 31 cases of primary hepatic carcinoma by using the methods of ELISA and immunohistochemistry separately. Among them, 10 cases were studied by the immunoelectromicroscopic technique . Result β-G was highly expressed both in the serum and carcinoma tissue in hepatic carcinoma patients and there was very significant difference as compared with the control group, (P < 0. 01 ). Conclusion The combined functional and morphological examination of β-G might be useful to the early discovery and early diagnose of hepatic carcinoma.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
1999年第1期42-43,共2页
Chinese Journal of Experimental Surgery
基金
辽宁省自然科学基金!962252
关键词
肝肿瘤
β葡萄糖醛酸酶
ELISA
Hepatic carcinoma β-glucuronidase ELISA Immunohistochemistry Immunoelectro-microscopy
