摘要
目的 探讨直肠癌彩色血流平均密度（MCVD）与微血管密度（MVD）的相关性及其与直肠癌浸润深度及淋巴转移的关系.方法 术前应用经直肠彩色血管能量成像计测MCVD,术后取组织标本以抗CD105单克隆抗体行免疫组织化学染色,计数MVD,分析MCVD与MVD的相关性及其与癌肿浸润深度及淋巴结转移的关系.结果 MCVD与MVD呈正相关（r=0.763,P＜0.01）.MCVD、MVD在肿瘤浸润深度及有无淋巴结转移上差异均有统计学意义（P＜0.05）.结论 MCVD能反映直肠癌的血供特点及病珲微血管分布,可间接反映直肠癌的病程进展,为术前选择有效治疗方案、评估预后提供参考信息.
Objective To explore the relationship of the mean color vessels density （MCVD） and pathologic microvessel density（MVD） in rectal cancers and their relation with T stags and lymph node metastasis.Methods MCVD were caculated preoperationly with transrectal color power angiography（TRCPA）.After operation MVD was assessed immunohistochemically using anti-CD105 monoclonal antibody.The relationships within MCVD, MVD and T stages and lymph node metastasis were analysed.Results There were positive correlation between MCVD and MVD （r=0.763, P〈0.01） in rectal cancer.There were significant difference of MCVD and MVD in both the depth of carcinoma invasion and metastasis of lymphatic nodes（ P〈0.05）.Conclusions MCVD can display features of the blood supply and distribution of pathologic microvessels and reflect the development of rectal cancers.MCVD is a credible index to choose available treatment and to evaluate prognosis before operation of rectal cancer.
出处
《中华超声影像学杂志》
CSCD
北大核心
2010年第6期503-505,共3页
Chinese Journal of Ultrasonography
