摘要
芥子碱对Ｏ－２和ＯＨ的清除效率达５０％时的质量浓度（ρ）分别为５ｍｇＬ－１和３３０ｍｇＬ－１，４０ｍｇＬ－１的芥子碱对Ｏ－２的清除效率即可达８９．７％，证明芥子碱是一Ｏ－２与ＯＨ的清除剂．分别以ρ为１０ｍｇＬ－１和５０ｍｇＬ－１芥子碱的培养基饲喂果蝇，对果蝇的最高寿命、平均寿命及半数寿命均有一定的延长作用，其中１０ｍｇＬ－１的芥子碱组可明显延长雄性果蝇的最高寿命（１１．９０％）、平均寿命（１１．２４％）及半数寿命（１７．２１％），两种浓度的芥子碱溶液对果蝇的平均寿命的延长作用的差异显著．芥子碱对果蝇的延寿作用有一定的性别差异。
It is reported that sinapine is a natural radiation protection substance distributed in Cruciferous plants. The scavenger effect of sinapine on superoxide anions (O - 2) and hydroxyl radicals ( OH ), and antiaging effect on Drosophila melanogaster were studied in this paper. The results indicated that sinapine could be used as efficient scavengers for O - 2 and OH . The mass concentrations ( ρ ) of sinapine in scavenging 50% O - 2 and OH are 5 mg L -1 and 330 mg L -1 , respectively. The scavenging efficiency of O - 2 by 40 mg L -1 sinapine is 89.7%. 10 mg L -1 and 50 mg L -1 of sinapine could effectively prolong the maximum life span, average life span and median life span of Drosophila melanogaster , and 10 mg L -1 of sinapine could increase the maximum life span (by 11.90% ), average life span (by 11.24% ) and median life span (by 17.21%) in male flies. The anti aging effect of sinapine on the males was better than that on the females.
出处
《应用与环境生物学报》
CAS
CSCD
1999年第1期32-35,共4页
Chinese Journal of Applied and Environmental Biology
基金
中国科学院上海分院择优经费项目
关键词
芥子碱
抗衰老
活性氧自由基
果蝇
sinapine
anti aging
oxygen free radicals
Drosophila melanogaster
