摘要
目的：探讨非小细胞肺癌的Ⅰ型细胞间粘附分子（ＩＣＡＭ－１）的表达与侵袭和转移间的关系。方法：用免疫组化技术检测了５２例非小细胞肺癌及转移淋巴结中ＩＣＡＭ－１的表达。结果：２０例伴淋巴结转移的肺癌中，１４例ＩＣＡＭ－１表达阳性，相应淋巴结转移灶１３例阳性。３２例无淋巴结转移的肺癌中仅有６例阳性。结论：肺癌细胞ＩＣＡＭ－１的表达可作为判断癌细胞的侵袭及转移的指标。
Objective To study the relationship of the intercellular adhesion molecule 1 (ICAM 1) expression in non small cell lung cancer(NSCLC) between its invasion type and metastasis type.Methods:ICAM 1 Expression in 52 cases of primary and metastatic NSCLC were studies on cytostat sections by means of immunohistochemistry.Results:There are 14 of 20 primary cancers and 13 of 20 lymph node metastasis Cancers showed strong ICAM 1 positive staining,whereas only 6 cases showed ICAM 1 positive in 32 non lymph node metastasis cancers.Conclusion:There is a good relationship on ICAM 1 expression between invasion and metastasis types in NSCLC.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1999年第1期26-27,共2页
Cancer Research on Prevention and Treatment
关键词
肺肿瘤
细胞间粘附分子
肿瘤转移
Lung carcinoma
Intercellular adhesion molecule-1
Neoplasm metastasis
