摘要
为对中国莱姆病螺旋体的宿主动物有所了解，于１９８７～１９９７年间，作者在中国１６个省（市、区）的山林地区，采用血清流行病学和病原学研究方法，对牛、羊、狗、野兔和野鼠进行了莱姆病的调查研究。结果显示在我国至少有牛、羊、狗、野鼠、野兔等５种动物中有莱姆病的感染存在。牛、羊和狗的感染率分别为１８．１８％～３２．６１％、１７．１２％～６１．２１％和３８．５０％～６０．００％。狗作为我国北方林区莱姆病螺旋体的主要生物媒介全沟硬蜱成虫的主要供血者之一，可能是较重要的宿主动物。从黑线姬鼠、棕背、花鼠、白腹鼠、社鼠、褐家鼠、针毛鼠、白腹巨鼠和华南兔等动物分离出２０株莱姆病螺旋体，尤其是从黑线姬鼠和白腹巨鼠的胎鼠分离到莱姆鼠病螺旋体，证实莱姆病螺旋体可通过胎盘垂直传播，这对莱姆病自然疫源地的维持和扩大有重要意义。野鼠的感染率在４１．１８％～８６．０５％间。血清学和病原学调查结果证实黑线姬鼠和棕背是中国莱姆病螺旋体的重要储存宿主。
From 1987 to 1997,the reservoir hosts of Borrelia burdorferi(B.b. )were investigated in 16 provinces,municipalities and autonomous regions of China.Seroepidemiological findings indicated that cattle,sheep,dogs and rats from forest areas had a high antibody titer for B.b. (B 31 ) with positive rates of 18 18%～32 61%,17 12%～61 21%,38 50%￣60 00% and 41 18%￣86 05% respectively .Using BSK medium,20 strains of B.b. were isolated from Apodemus agrarius,Clethrionomys rufocanus,Eutamias sibiricus,Rattus coxingi,Rattus norvegicus,Rattus edwardsi,Rattus confucianus,Rattus fulvescens and Caprolagus sinensis.These spirochetal strains were identified as B.b. by indirect immunofluorescence assay using species and genus specific monoclonal antibodies.Vertical transmission of B.b. was confirmed with B.b. isolated from foetuses of Apodemus agrarius and Rattus edwardsi.The results showed that lyme disease spirochetes, B.b. ,might be naturally maintained in an enzootic cycle by transplacental transmission.Apodemus agrarius and Clethrionomys rufocanus might serve as major reservoir hosts for B.b.in China.
出处
《卫生研究》
CAS
CSCD
北大核心
1999年第1期7-9,共3页
Journal of Hygiene Research
基金
卫生部科研基金
关键词
莱姆病
莱姆病螺旋体
黑线姬鼠
棕背Ping
lyme disease,borrelia burgdorferi,reservoir host, apodemus agrarius,clethrionomys rufocanus
