摘要
目的：为初步掌握黑龙江省小兴安岭林区动物莱姆病分布情况。方法：于1995年7月用鼠笼捕获野鼠30只，采用间接免疫荧光抗体法调查鼠血清抗莱姆病螺旋体抗体。用BSK培养基从鼠脏器分离病原。结果：阳性共8只，阳性率26.67％；其中优势种属野鼠阳性率达31．36％；从棕背和花鼠各分离出1株莱姆病螺旋体。新分离株的单克隆抗体反应与国内分离株SR1相同，与美国B(31)有区别，对H(6831)呈阴性反应。结论：鼠型啮齿动物可能是莱姆病螺旋体的动物宿主，属野鼠则是重要动物宿主。
In July, 1995, the animal reservoirs of Lyme disease spirochetes was investigated in the Small Xing-An Mountains of Heilongjiang province, China. of 30 rats, 8 rats had a signifcant antibody titer against Borrelia burgdorferi and Clethrionomys rufocanus was prevailing in this region. Two Strains of Borrelia burgdorferi were cultivated from the kidney of Clehrionomys rufocanus and the bladder of Eutamias sibricus and these isolates were distinguished between China and USA by monoclonal antibodies (H5332, H6831 and H9724). These studies indicated that Clethrionomys rufocanus be primary reservoir of Borrelia burgdorferi and this region be an endemic area of Lyme disease.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
1997年第3期210-212,共3页
Chinese Journal of Vector Biology and Control
