期刊文献+

来得时对老年2型糖尿病合并冠心病患者血糖波动的疗效观察 被引量:3

暂未订购
导出
摘要 目的比较来得时(甘精胰岛素)和中效低精蛋白生物合成人胰岛素(NPH)对老年2型糖尿病(T2DM)合并冠心病患者血糖波动的疗效和安全性。方法41例口服降糖药治疗但血糖控制未达标的老年T2DM合并冠心病患者,随机分为来得时治疗组(n=21)和NPH治疗组(n=20),分别于每日睡前增加1次来得时、NPH皮下注射。对比分析空腹血糖(FBG)、糖化血红蛋白(HbA1 c)和低血糖的发生情况。结果两组治疗后FBG、HBA1 c、FBG达标时间、低血糖发生率比较差异有统计学意义(P<0.05)。结论来得时优于NPH,能有效、更安全的控制老年T2DM合并冠心病患者的血糖波动。
出处 《山东医药》 CAS 北大核心 2010年第20期55-56,共2页 Shandong Medical Journal
基金 辽宁省科技攻关课题资助(2007225021)
  • 相关文献

参考文献7

  • 1Abdul-Ghani MA,Abdul-Ghani T,Ali N,et al.One-hour plasma glucose concentration and the metabolic syndrome identify subjects at high risk for future type 2 diabetes[J].Diabetes Care,2008,31(8):1650-1655.
  • 2Nathan DM,Buse JB,Davidson MB,et al.Management of hyperglycemia in type 2 diabetes:A consensus algorithm for the initiation and adjustment of therapy:a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes[J].Diabetes Care,2006,29(8):1963-1972.
  • 3Bossoni S,Mazziotti G,Gazzaruso C,et al.Relationship between instrumental activities of daily living and blood glucose control in elderly subjects with type 2 diabetes[J].Age Ageing,2008,37(2):222-225.
  • 4Dorkhan M,Dencker M,Stagmo M,et al.Effect of pioglitazone versus insulin glargine on cardiac size,function,and measures of fluid retention in patients with type 2 diabetes[J].Cardiovasc Diabetol,2009,8:15.
  • 5Dornhorst A,Lüddeke HJ,Koenen C,et al.Transferring to insulin detemir from NPH insulin or insulin glargine in type 2 diabetes patients on basal-only therapy with oral antidiabetic drugs improves glycaemic control and reduces weight gain and risk of hypoglycaemia:14-week follow-up data from PREDICTIVE[J].Diabetes Obes Metab,2008,10(1):75-81.
  • 6Buse JB,Wolffenbuttel BH,Herman WH,et al.DURAbility of basal versus lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results:safety and efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral antihyperglycemic drugs in patients with type 2 diabetes[J].Diabetes Care,2009,32(6):1007-1013.
  • 7Dailey G,Strange P.Lower severe hypoglycemia risk:insulin glargine versus NPH insulin in type 2 diabetes[J].Am J Manag Care,2008,14(1):25-30.

同被引文献19

引证文献3

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部