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姬松茸子实体多糖ABMB3对小鼠免疫功能的影响 被引量：12

Effect of a Polysaccharide Fraction from Agaricus blazei Fruit Bodies on Murine Immunological Functions
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摘要 姬松茸(Agaricus blazei)子实体经沸水提取、乙醇沉淀、DEAE-Sepharose Fast Flow和Sephacryl S-300HR层析获得多糖ABMB3,研究表明:200μg/mL ABMB3可以刺激小鼠淋巴细胞分泌免疫球蛋白G(Immunoglobulin G,IgG)、IgM以及细胞因子白细胞介素6(Interleukin6,IL-6)、干扰素(Interferon,IFN)、IL-2和IL-4,说明ABMB3可以提高小鼠的免疫功能。 A polysaccharide fraction,ABMB3,was obtained from fruit bodies of Agaricus blazei following extraction with boiling water,ethanol precipitation ,ion exchange chromatography （DEAE-Sepharose Fast Flow） and gel filtration chromatography （Sephacryl S-300HR）. ABMB3 at a concentration of 200 μg/mL improved murine immunological functions by enhancing levels of IgG,IgM,IL-6,IFNg,IL-2 and IL-4.
作者 贾薇 严淑玲 樊华
机构地区 国家食用菌工程技术研究中心 柏林夏洛蒂医科大学分子生物学和生物化学研究所
出处 《食用菌学报》 北大核心 2010年第1期65-68,共4页 Acta Edulis Fungi
基金 德国Bundes ministriumfr Forschungund Technologie Bonn科研基金资助项目(编号:SFB366)的部分研究内容
关键词 姬松茸 多糖 免疫活性 Agaricus blazei polysaccharide immunological function
分类号 S567.39 [农业科学—中草药栽培]
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参考文献9

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二级参考文献8

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食用菌学报
2010年 第1期

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