摘要
目的通过检测龈沟液(GCF)中可溶性细胞间粘附分子-1(sICAM-1)水平的变化,探讨盐酸米诺环素缓释软膏对慢性牙周炎的临床疗效。方法 28例慢性牙周炎(CP)患者,每人选择一颗磨牙作为实验组(基础治疗+盐酸米诺环素缓释软膏治疗组);以对侧同名牙作为对照组(基础治疗组)。分别在治疗前、治疗后4周时进行临床检查和sI-CAM-1浓度的测定。结果第4周时,实验组sICAM-1浓度、牙周袋探诊深度(PD)与对照组相比差异有统计学意义(P<0.05)。结论盐酸米诺环素缓释软膏对牙周基础治疗有良好的辅助疗效。
Objective To study the level of sICAM-1 in gingival crevicular fluid of chornic periodontitis with minoeyeline-HCL sustained release unguent treatment.Methods Two molars were selected randomly from each mouth of 28 patients with chornic periodontitis,and were divided into groups：test group（initial therapy＋minoeyeline-HCL sustained release unguent）and control group（initial therapy）.The level of sICAM-1 were detected before and after treatment.Results The sICAM-1 level of test group declined significantly than control group.Conclusion Minoeyeline-HCL sustained release unguent may imporve the effects of initial therapy to chornic periodontitis.
出处
《四川医学》
CAS
2010年第5期579-581,共3页
Sichuan Medical Journal
