摘要
目的分析顺行性溶栓治疗晚期恶性肿瘤并发深静脉血栓形成(Trousseau综合征)的疗效。方法15例以恶性肿瘤首诊入院,肿瘤围手术期及放化疗期发生DVT;4例以DVT首诊入院,其中3例发现既往患恶性肿瘤;1例经影像学检查发现腹膜后恶性肿瘤。深静脉血栓形成经彩色多普勒外周血管超声检查确诊。采用尿激酶顺行性溶栓,同时全身应用低分子右旋糖苷,低分子肝素钙皮下注射,服用小剂量肠溶阿司匹林及中医中药等措施治疗。结果本组无围手术期死亡病例。1例因疗效果不明显而放弃治疗自动出院;其余18例均获不同程度缓解,获临床治愈效果。结论提示对于原因不明的DVT,应疑及Trousseau综合征的可能;顺行性溶栓治疗效果可靠。
Objective To analyze the clinical efficacy of anterograde thrombolytic treatment in malignant tumor complicated with deep venous thrombosis （Trousseau syndrome）. Methods 15 patients were admitted to hospital with malignant tumor for the first diagnosis while DVT occurred during cancer treatment. Another 4 patients had DVT diagnosis in the first hospitalization,of which 3 patients with medical history of malignant tumor. The last one case showed retroperitoneal malignant tumor by imaging examination. Deep venous thrombosis diagnosis was confirmed by color Doppler ultrasound. Anterograde thrombolysis with urokinase was adopted while all kinds of treatment were used including systemically using low-molecular weight dextran,low-molecular weight calciparine subcutaneous injection,taking low-dose enteric-coated aspirin as well as traditional Chinese medicine. Results This group had no patient death during perioperative period. One patient gave up the treatment to be automatically discharged from hospital. The other 18 patients had varying degrees of ease and had the effective clinical cure. Conclusion It should be doubt about Trousseau syndrome for unexplained DVT,and the effect of the anterograde thrombolytic is reliable.
出处
《当代医学》
2010年第11期202-203,共2页
Contemporary Medicine
