摘要
目的:评估胰岛素抵抗(IR)对急性ST段抬高心肌梗死(STEMI)患者院内预后的影响。方法:入选148例STEMI患者,分为胰岛素抵抗组(IR组)和非胰岛素抵抗组(NIR组),比较两组的临床特点和院内预后。结果:IR组合并高血压较NIR组多,且入院时血压也较高。IR组患者冠脉狭窄程度较NIR组严重,心功能不全发生率、住院期间脑血管意外、院内死亡率也显著增高。结论:STEMI合并IR患者冠脉病变程度严重、住院死亡及脑血管意外发生率较NIR患者显著增高,提示IR是预测STEMI患者院内预后的重要因素之一。
Objective： To evaluate the outcomes during hospitalization in patients suffering from ST-elevation acute myocardial infarction （STEMI） and insulin resistance. Methods： We enrolled t48 patients suffering from STEMI. The patients were divided into IR group （38 patients with insulin resistance） and NIR group （110 patients without insulin resistance）. Clinical variables and outcomes during hospitalization were compared. Results： Compared with patients in N1R group, patients in IR group were more likely to have hypertention. The degree of coronary stenosis in IR group was more severe than that in NIR group. IR group patients were also more likely to have cardiac insufficiency and cerebrovascular accidents. Mortahty was markedly increased in IR group. Conclusions： Insulin resistance may predict the severity of coronary artery lesions in STEMI patients. Mortality during hospitalization was increased in patients with insulin resistance. This study indicates that insulin resistance is one of the factors that can predict the in-hospital prognosis in patients with STEMI.
出处
《国际心血管病杂志》
2010年第3期173-176,共4页
International Journal of Cardiovascular Disease
关键词
急性心肌梗死
胰岛素抵抗
预后
Acute myocardial infarction
Insulin resistance
Prognosis
