摘要
探讨雪茶提取物[Extractive of Thamnolia vermicularis(ACH)Asahina]的抗疲劳作用效果。方法:取小鼠,随机分组,实验设高、低剂量组分、空白组、阳性药物组。雪茶提取物应用灌胃给药方法,通过各组小鼠负重游泳实验,对雪茶的抗疲劳作用进行物理性研究;通过测试小鼠游泳后和静置一定时间后血液中血糖变化,血乳酸变化,肝糖原含量及血尿素含量,对雪茶的抗疲劳作用进行相关生理指标研究。结果:雪茶提取物显著增加了小鼠的游泳时间,血液和肝脏中各个指标的变化具有良性效果。结论:雪茶提取物有提高小鼠的抗疲劳作用的效果,并在一定浓度范围内呈剂量依赖性显著改善小鼠抗疲劳能力。
Objective： The discussion of the anti-fatigue function of extractive of Thamnolia vermicularis（ACH）Asahina. Methods： Devide mouses into four random allocations by high dosage,low dosage,non-dosage and masculine medication. And apply medication by intragastric administration. Then execute physical research of the function by burden-swimming experiments of mouses. At last,execute research of physiological index by examine the change of the content of GLU,BLA,glycogen and BUN in blood after the burden-swimming experiments. Results： In certain concentration rate,the extractive of Thamnolia vermicularis,notably lengthen the time of the mouses＇swimming time,and it improves all the index of the blood and liver that be detected. Conclusion： The extractive of Thamnolia vermicularis can apply the anti-fatigue function with mouses. And it improve the anti-fatigue function of mouses in dose-dependent way
出处
《中医药学报》
CAS
2010年第2期29-32,共4页
Acta Chinese Medicine and Pharmacology
基金
北京市科技新星计划资助项目(编号2008118)
"985"工程资助项目(编号:CUN9850303)
关键词
雪茶提取物
血乳酸
血糖
肝糖原
血尿素氮
抗疲劳
Extractive of Thamnolia vermicularis
BLA
GLU
Glycogen
BUN
Anti-fatigue
