摘要
目的观察脑电双频指数(BIS)指导心脏体外循环(CPB)手术麻醉的临床效果。方法选择2007年9月至2009年9月在我院行择期手术的先天性心脏病患者50例,分为BIS组和对照组各25例,BIS组予BIS监测控制异丙酚泵入速度使BIS值维持在45±5,对照组持续静脉泵入异丙酚2～3mg/(kg.h)。记录患者开放静脉通路时(T0)、麻醉诱导后10min(T1)、主动脉阻断后20min(T2)和主动脉开放后20min(T3)4个时点平均动脉压(MAP)、心率(HR)和中心静脉压(CVP)及患者CPB时间、主动脉阻断时间、术后拔管时间、重症监护室(ICU)停留时间。结果两组患者各时点MAP、HR和CVP、心脏CPB时间及主动脉阻断时间差异均无统计学意义(P>0.05);BIS组术后拔管时间和ICU停留时间短于对照组(P<0.05)。结论在CPB手术麻醉中,采用BIS监控可以减少术后拔管时间及ICU停留时间,有利于患者的早期恢复。
Objective To observe the clinical effect of bispectral index （ BIS} in anaesthesia during cardiopulmonary bypass. Methods Fifty patients with congenital heart disease from September 2007 to September 2009 were randomly divided to two groups. The BIS group was controlled to maintain the BIS value at about 45 ± 5. Patients in control group were pumped Propofol （2 -3 mg. kg-1. h^-1 ） persistently. MAP, CVP and HR were monitored when open venous channel （TO） , at 10 rain after anesthesia induction （TI） , at 20 min after aorta cross-clamping （ T2 ） and at 20 min after releasing of aorta cross-clamping T3）. The CPB time, aortic cross-clamping time, postoperative extubation time and the residence time in ICU were recorded. Results MAP, CVP, HR, aortic cross-clamping time and CPB time between the two groups were not different significantly （ P 〉 0. 05 ）. The postoperative extubation time and residence time in ICU of BIS group were shorter than those of control group （ P 〈 0. 05 ）. Conclusion BIS monitoring in cardiopulmonary bypass is benefit for patients＇ early recovery.
出处
《实用医院临床杂志》
2010年第3期37-38,共2页
Practical Journal of Clinical Medicine
关键词
脑电双频指数
心脏
体外循环
异丙酚
Bispectral index
Heart
Cardiopulmonary bypass
Propofol
