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TCT和阴道镜活检在宫颈癌前病变诊断中的价值 被引量:13

The value of TCT and colposcope biopsy in diagnosis of precancerous lesions of uterine cervix.
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摘要 目的对TCT和阴道镜活检病理结果进行对比分析,并进一步探讨二者在宫颈癌前病变诊断中的价值。方法回顾性分析209例阳性宫颈的液基细胞学和对应的阴道镜活检病理检查的结果,进行对比研究。结果209例阳性TCT病例中,ASCUS97例(46.41%)、LSIL56例(26.79%)、HSIL52例(24.88%)、鳞状细胞癌4例(1.92%)。209例经阴道镜下多点活检,病理诊断如下:炎症47例(22.49%)、CINI级70例(33.49%)、CINII级32例(15.31%)、CINIII级51例(24.40%)、浸润癌9例(4.31%)。与病理结果比较,209例TCT报告中,LSIL的诊断符合率58.93%(33/56),HSIL及以上病变的诊断符合率92.86%(52/56),LSIL与HSIL及以上搞变的诊断符合率比较,差异有显著性(x^2=7.58,P〈0.01)。结论TCT作为宫颈病变的初筛手段,能够发现大量的宫颈癌前病变患者,结合阴道镜下活组织检查,大大提高了宫颈癌前病变的检出率。 Objective To making a contrasting analysis of TCT and the pathology result of Colposcope biopsy, and discussing their value further in diagnosis of precancerous lesions of uterine cervix . Methods Analyzing retrospectively TCT of positive cervix of 209 cases and corresponding pathology result of colposeope biopsy. Results Among the 209 positive TCT cases ,97 cases are ASCUS(46.41% ) , 56 cases are LSIL (26.79%), 52 cases are HSIL(24.88% ) ,and 4 cases are Epidermoid carcinoma( 1.92% ). Through multiple punch biopsy under colposcope,pathology diagnosis are as below : inflammation 47cases ( 22.49% ) , CIN I 70cases ( 33.49% ) , CIN II 32cases ( 15.31% ), CIN III 52cases (24.88 % ) ,infiltrating carcinoma 9cases (4.32%) . Contrasting with pathology result, among the TCT report of 209 cases, the diagnosis coincidence for LSIL is 58.93% (33/56), but for HSIL and the above - mentioned diagnosis of pathological changes, it is 92.86% (52/56), which showing obvious deference. (X^2 = 7.58, P 〈 0.01 ). Conclusion As a preliminary screening means of pathological process of cervix,TCT can find a lot of sufferers from precancerous lesions of uterine cervix, which greatly improve the relevance ratio, combining colposcope biopsy.
出处 《中外医学研究》 2010年第2期3-4,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 TCT宫颈癌前病变 阴道镜活检 TCT Cervical preinvasive lesion Colposcope biopsy
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