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不同来源精子对卵胞浆内单精子注射助孕结局的影响 被引量:13

Outcome of intracytoplasmic spem injection using different sources sperm
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摘要 目的探讨精液精子、附睾精子和睾丸精子对卵胞浆内单精子注射(ICSI)助孕结局的影响。方法回顾性分析因男方因素寻求ICSI助孕的283个周期的临床资料,其中精液精子行ICSI组174个周期,附睾精子行ICSI组55个周期,睾丸精子行ICSI组54个周期,比较3组的受精率、卵裂率、临床妊娠率、早期流产率。结果3组患者的受精率、临床妊娠率、早期流产率比较差异无统计学意义(P>0.05),而使用附睾精子的胚胎卵裂率低于精液精子(90.95%vs94.02%,P<0.05)。结论若能够获得可移植的胚胎,精液精子、附睾精子和睾丸精子对ICSI助孕结局无明显影响;附睾精子行ICSI形成的胚胎,其发育潜力可能低于精液精子行ICSI形成的胚胎。 Objective To compare the outcome in intracytoplasmic spem injection using sperm from ejaculates semen,epididymal sperm and testicular sperm.Methods Reviewed the treatment results of 283 cycles of ICSI,ejaculate sperm group underwent 174 cycles of ICSI,epididymal sperm group underwent 55 cycles of ICSI,testicular sperm group underwent 54 cycles of ICSI,We compared 3 groups fertilization rate,cleavage rate,pregnancy rate and early abortion rate.Results No difference was observed among 3 groups in fertilization rate,pregnancy rate and early abortion rate,but the cleavage rate had statistical significance(90.95% vs 94.02%,P〈0.05).Conclusion There is no significant difference in fertilization and pregnancy outcome in intracytoplasmic sperm injection using ejaculate sperm,epididymal sperm and testicular sperm,the development potential of embryo from intracytoplasmic spem injection using epididymal sperm may be lower than the ejaculate sperm's.
出处 《安徽医科大学学报》 CAS 北大核心 2010年第1期112-114,共3页 Acta Universitatis Medicinalis Anhui
关键词 精子注射 细胞质内 无精子症 sperm injections intracytoplasmic azoospermia
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参考文献6

  • 1Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Male Reproduction and Urology. Evaluation of the azoospermic male [ J ]. Fertil Steril, 2008,90 ( 5 Suppl) : S74 - 7.
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二级参考文献6

  • 1张文香,曹云霞,周平,章志国,赵济华.不同来源的精子显微受精治疗男性不育[J].安徽医科大学学报,2004,39(6):468-470. 被引量:8
  • 2Govaerts I,Devreker F,Koenig I,et al.Comparison of pregnancy outcome after intracytoplasmic sperm injection and in vitro fertilization[J].Hum Reprod,1998,13(6):1514-8.
  • 3Bonduelle M,Liebaers I,Deketelaere V,et al.Neonatal data on a cohort of 2889 infants born after ICSI(1991-1999) and of 2995 infants born after IVF(1983-1999)[J].Hum Reprod,2002,17(3):671-94
  • 4Bonduelle M,Aytoz A,Van Assche E,et al.Incidence of chromosomal aberrations in children born after assisted reproduction through intracytoplasmic sperm injection[J].Hum Reprod,1998,13(4):781-2.
  • 5Wennerholm U,Bergh C,Hamberger L,et al.Incidence of congenital malformations in children born after ICSI[J].Hum Reprod,2000,15(4):944-8.
  • 6魏兆莲,曹云霞,丛林,赵济华,李芬,周平,余敏.体外授精胚胎移植在不孕症治疗中的应用[J].安徽医科大学学报,2001,36(4):299-300. 被引量:8

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