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反复呼吸道感染患儿肺脾气虚证与免疫功能及T细胞亚群相关分析 被引量:6

Correlation analysis between syndrome of qi deficiency of both lung and spleen and immune function, T cell subset of child with repeated respiratory infection
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摘要 目的:探讨反复呼吸道感染患儿肺脾气虚证与机体免疫功能及T细胞亚群之间的相关性。方法:按复感儿诊断标准,筛选肺脾气虚证患儿30例,抽取空腹血,分别检测患儿血清免疫球蛋白(IgG、IgA、IgM、IgE)及T细胞亚群(CD3、CD4、CD8),并与健康儿15名进行对照。结果:复感儿血清IgG、IgA明显低于对照组(P均<0.001),IgE高于对照组(P<0.05),而IgM在两组间差异无统计学意义(P>0.05);复感儿CD3、CD4、CD4/CD8明显低于对照组(P均<0.001),CD8却明显高于对照组(P<0.001)。结论:肺脾气虚证患儿存在着某些免疫功能失调。 Objective: To analyze the correlation of syndrome of qi deficiency of both lung and spleen and immune function, T cell subset of child with repeated respiratory infection. Methods: 30 Cases of syndrome of qi deficiency of both lung and spleen of repeated respiratory infection child were selected according to the diagnostic criteria of repeated respiratory infection child. The indexes of Ig G, Ig A, Ig M, Ig E, CD3, CD4, CD8 in fasting blood were detected. Results: Compared with healthy child group, the IgG, IgA, CD3, CD4, CD4/CD8 decreased obviously in repeated respiratory infection group (P〈0.001), the IgE and CD8 increased significantly (P〈0.001), and there was no statistical difference of IgMbetween the two groups. Conclusion: There was immunological functional disorder of child with qi deficiency of both lung and splee.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2010年第2期315-316,共2页 China Journal of Traditional Chinese Medicine and Pharmacy
关键词 反复呼吸道感染患儿 肺脾气虚证 免疫功能 T细胞亚群 临床研究 Child with repeated respiratory infection Syndrome of qi deficiency of both lung and spleen Immune function T cell subset Clinic Study
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参考文献2

  • 1胡仪吉.反复呼吸道感染的诊断标准[J].中华儿科杂志,1988,26(1):41-41.
  • 2沈自尹 王文健.中医虚证辨证参考标准[J].中西医结合杂志,1986,6(10):598-598.

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