摘要
分析三七总皂苷注射液致不良反应(ADR)的发生特点及相关因素,为临床合理使用三七总皂苷提供参考。对国内15年来发表的103例三七总皂苷致不良反应病例进行回顾性分析。在103例ADR报告中,>60岁的ADR发生率最高(41.7%);ADR最为常见的临床表现为药疹(50.5%);其次为过敏反应(20.4%)以及过敏性休克(9.7%)。ADR发生与诸多因素有关。严格用药指征,用药前详细询问过敏史,加强药物不良反应监测,促进临床合理用药。
To analyze the characteristics and relative factors of adverse drug reactions （ADR） induced by sanqizongzaogan injecktion, in order to provide reference for the clinical use of sanqizongzaogan injecktion properly. The 103 reported cases of ADR induced by sanqizongzaogan injecktion in China over 15 years were retrospectively analyzed. The 103 ADR cases, 41.7% occurred in patients aged above 60. The most common presentation of ADR was durg eruption, followed by allergic reactions （ 20. 4% ） and allergic shock（9. 7% ）. The occurrence of ADR is affected by many factors. We should control the drug indication strictly, check patients drug allergy history carefully before prescription, monitor ADR afterwards, promote clinical rational drug-usage.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2010年第2期237-239,共3页
China Journal of Chinese Materia Medica
