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百例药疹的综合分析 被引量:11

Comprehensive analysis of drug eruption in one hundred patients
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摘要 目的 :了解近年来临床用药与药疹发生的关系。方法 :随机抽取我院皮肤科 1998年 10月~2 0 0 0年 10月住院病历 4 2 8份 ,其中明确诊断为药疹的病历 10 0份 ,分析病人过敏史、潜伏期、药疹类型、致敏药物种类及其他相互关系。结果 :百例药疹涉及药品 4 3种 ,明确为 1种致敏药物为 5 7% ,2种可疑致敏药物为 2 8% ,3种以上可疑致敏药物为9%。结论 :致敏药物排在前 3位的是抗生素、解热镇痛药。 AIM: To investigate the relationships between recent clinical drugs and occurrence of drug eruptions. METHODS: Randomly draw hospitalization clinical history four hundred and twenty-eight dodla of patients from the department of dermatology in our hospital from Oct. 1998 to Oct. 2000. Among which one hundred patients were confirmed as drug eruption. Then the patients' allergic history, latent period, drug eruption types, sensitization drug categories, and their relationships were analysed. RESULTS: The drugs causing drug eruption include forty-three drugs, 57 % patients were caused by one specific kind of drug, 28 %patients were probably caused by two kinds of drugs, and 9% patients were caused by three or more than three kinds of durgs. CONCLUSION: The drugs causing drug eruption and ranking on the first three were antibiotics, antipyretic analgesics, and Chinese medicine.
作者 张碧玫 宋颖
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2002年第12期758-760,共3页 Chinese Journal of New Drugs and Clinical Remedies
关键词 药疹 药物过敏 治疗 转归 drug durg eruption durg hypersensitivity
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参考文献3

  • 1杨鑫海.药物性皮炎130例临床分析[J].临床皮肤科杂志,1983,12(6):323-323.
  • 2陈红清,陈志强,岳晓玉,徐文严.202例药疹住院病例临床特征分析[J].中华皮肤科杂志,1999,32(2):130-130. 被引量:65
  • 3刘琴.阿莫仙致药疹29例临床分析[J].临床皮肤科杂志,1997,26(2):137-137.

二级参考文献4

  • 1陈新谦 金有豫.新编药物学(第14版)[M].北京:人民卫生出版社,1997.487.
  • 2赵辩.药疹.临床皮肤病学(第2版)[M].南京:江苏科学技术出版社,1989.529.
  • 3陈新谦,新编药物学(第14版),1997年,1页
  • 4赵辨,临床皮肤病学(第2版),1989年,529页

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