摘要
为探讨准分子激光角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅｋｅｒａｔｅｃｔｏｍｙ，ＰＲＫ）后角膜上皮下雾状混浊（ｈａｚｅ）的原因及影响因素，对ＰＲＫ后６个月时屈光度在－１．００～－１８．５０Ｄ的３１６例（６１５只眼）近视眼的ｈａｚｅ相关因素进行观察和比较。结果：ＰＲＫ后６个月时ｈａｚｅ发生率为４４．７％，１级或以上ｈａｚｅ为１３．３％。ｈａｚｅ的发生率及密度随屈光度增高而增加（Ｐ＜０．０００１），也随切削深度的增加而增加（Ｐ＜０．０００１），术前非接触眼压超过１８ｍｍＨｇ者，ｈａｚｅ的发生率和密度增加（Ｐ＜０．００５），男性较易发生ｈａｚｅ（Ｐ＝０．０００１），与年龄呈负相关（Ｐ＜０．０５）。而角膜厚度、术前戴用接触镜及散光对ｈａｚｅ的影响不显著。结论：高度近视（＞－６．０Ｄ）和过深的切削（＞８０μｍ）是引起ｈａｚｅ的主要原因。术前眼压偏高、年龄偏低对ｈａｚｅ也有明显影响。
Objective:To identify the cause and predisposing factors of subepithelial corneal haze after excimer laser photorefractive keratectomy(PRK) .Methods:Six handred and fifteen myopic eyes with refractive errors ranged from -1 00 to -18 50D (spherical equivalent)were followed up for more than six months after PRK and the factors related to haze were analyzed and compared.Results:At six months,the overall frequency of clinically significant haze was 44 7%,but the frequency of haze grade 1 or more was 13 3%.The incidence and density of haze are statistically greater with higher refractive errors(P<0 0001),higher ablation depth(P<0 0001),higher preoperative intraocular pressure(>18mmHg,noncontact tonometer)(P<0 005)and in males(P=0 0001).Haze is negtively related age(P<0 05).But no difference was found related astigmatism,corneal thickness and contact lens weared preoperatively.Conclusions:Higher myopia(>-6 0D) and deeper ablation(>80μm)are main causes of haze.Higher preoperative intraocular pressure and lower age also obviously influence haze.We should be cautious about PRK on high myopia.
出处
《中国实用眼科杂志》
CSCD
1998年第9期558-560,共3页
Chinese Journal of Practical Ophthalmology
