摘要
目的:探讨了卵巢癌患者手术治疗前后血清TNF-α、SA和SIL-2R水平的变化及意义。方法:应用放射免疫分析、分光光度计法和酶免法对32例卵巢癌患者进行了手术治疗前后血清TNF-α、SA和SIL-2R检测,并与35名正常健康人作比较。结果:在手术前卵巢癌患者血清TNF-α、SA和SIL-2R水平均非常显著地高于正常人组(P<0.01),手术治疗3个月后则与正常人组比较无显著性差异(P>0.05)。结论:卵巢癌患者血清TNF-α、SA和SIL-2R的含量与该病的发生和发展密切相关。
Objective To explore the clinical significance of changes of serum TNF-α,sialicacid（SA） and SIL-2R contents after operation in patients with ovarian cancer.Methods Serum contents of TNF-α（with RIA） SA（with spectrometry） and SIL-2R（with ELISA） were measured in 32 patients with ovarian cancer both before and after operation as well as in 35 controls.Results Before operation,serum levels of TNF-α,SA and SIL-2R in patients with ovarian cancer were significantly higher than those in controls（P〈0.01）.Three months after operation the levels dropped markedly to approaching normal vs control（P〉0.05）.Conclusion The serum contents of TNF-α,SA and SIL-2R in patients with ovanian cancer closely related to the progress of the disease.
出处
《放射免疫学杂志》
CAS
2009年第6期588-589,共2页
Journal of Radioimmanology
关键词
卵巢癌
肿瘤坏死因子-α
唾液酸
白细胞介素-2受体
ovarian cancer
tumor necrosis factor-α（TNF-α）
sialic acid（SA）
interleukin-2 receptors（SIL-2R）
