摘要
目的 :探讨了肺癌患者血清中IL - 6、IL - 8和TNF含量的变化。方法 :应用酶联免疫吸附法和放免法测定了 4 0例肺癌患者血清中IL - 6、IL - 8和TNF含量 ,且与 35名正常健康人作比较。结果 :肺癌患者血清中IL - 6、IL - 8和TNF水平均非常显著地高于正常人 (P <0 0 1) ,术后IL - 6、IL - 8和TNF水平下降。结论 :测定肺癌患者血清中IL - 6、IL - 8和TNF含量对判断患者的免疫状态有一定的临床价值。
Objective To investigate the changes of serum IL-6、 IL-8 and TNF contents after surgery in patients with lung cancer. Methods Serum IL-6、IL-8 (with ELISA) and TNF (with RIA) contents were determined both before and after surgery in 40 patients with lung cancer as well as in 35 controls. Results Serum IL-6、IL-8 and TNF levels were significantly higher in patients with lung cancer before surgery than those in the controls (P<0.01). After surgery, those levels dropped markedly, approaching normal. Conclusion Changes of serum IL-6、 IL-8 and TNF levels after surgery might reflect improvement of cellular immuno-function after decrease of tumor burden.
出处
《放射免疫学杂志》
CAS
2004年第5期354-355,共2页
Journal of Radioimmanology
