摘要
目的对茜草科拉拉藤属植物蓬子菜(Galium verumL.)全草的体积分数为95%的乙醇溶液提取物进行分离并鉴定。方法采用硅胶柱色谱等方法分离化学成分,1H-NMR、13C-NMR等方法进行结构鉴定。结果从体积分数为95%的乙醇溶液提取物中分离得到6个化合物,分别鉴定为2,5-二羟基-1-甲氧基-蒽醌(2,5-dihydroxy-1-methoxyanthraquinone,1)、1-羟基-2-羟甲基-3-甲氧基-蒽醌(1-hydroxy-2-hydroxymethy-3-methoxyanthraquinine,2)、环烯醚萜内酯(morindolide,3)、水晶兰苷(monotropein,4)、去乙酰车叶草苷酸(deacetylasperulosidic acid,5)、6α-羟基-京尼平苷(6α-hydrox-ygeniposide,6)。结论化合物1、2、3为从本属植物中首次分离得到。
Objective To investigate the chemical constituents of the 95%(φ)EtOH extract of Galium verum L..Methods The constituents were isolated by silica gel column chromatography and the 1H-NMR,13C-NMR spectroscopic analysis were employed for the structural elucidation.Results Compounds 1-6 were obtained and their structures were identified as 2,5-dihydroxy-l-methoxyanthraquinone(1),1-hydroxy-2-hydroxymethy-3-methoxyanthraquinine(2),morindolide(3),monotropein(4),deacetylasperulosidic acid(5),6α-hydroxygeniposide(6).Conclusions Among them,compounds 1-3 are isolated from this genus for the first time.
作者
赵春超
邵建华
张玉伟
曹丹丹
李铣
ZHAO Chun chao;SHAO Jian-hua;ZHANG Yu-wei;CAO Dan-dan;LI Xian(College of Bioscience and Biotechnology,Yangzhou University,Yangzhou 225009,China;School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China)
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2009年第11期904-906,共3页
Journal of Shenyang Pharmaceutical University
关键词
茜草科
蓬子菜
化学成分
结构鉴定
Rubiaceae
Galium verum L.
chemical constituent
structure identification
