摘要
信号转导及转录活化因子3（STAT3）是STAT家族成员之一，也是肿瘤组织中的常见通路。STAT3与肿瘤的增生、凋亡、侵袭、迁徙、血管生成和免疫逃逸等关联。因此STAT3信号通道成为肿瘤治疗的一个潜在的作用靶点。
STAT3, as a member of signal transducers and activators of transcription （STATs） family, which has been recognized as one of the common pathways in cancer cells. STAT3 has been found in many tumor ceils that are critical to cell survival, cell proliferation, invasion, angiogenesis and immune evasion. Thus, STAT3 signaling pathway may be a potential therapeutic target for tumor metastasis.
出处
《肿瘤研究与临床》
CAS
2009年第11期789-792,共4页
Cancer Research and Clinic
基金
上海市教委基金（05BZ04）
