摘要
【目的】观察养肝活血法治疗多发性硬化(multiple sclerosis,MS)合并周围神经病变的疗效。【方法】对26例多发性硬化合并周围神经病变患者,在常规西药治疗的基础上加用养肝活血中药治疗,并在治疗前、治疗后1年分别进行周围神经损害临床症状体征观察、神经功能状态评分(EDSS评分)、肌电图(EMG)检查,比较周围神经损害临床症状体征、EDSS评分、运动神经及感觉神经传导、F波潜伏期及出现率的差异性。【结果】治疗后1年周围神经损害临床症状明显改善,EDSS评分下降,运动神经及感觉神经潜伏期缩短,传导速度增快,F波出现率增多、潜伏期缩短(P(0.05或P(0.01)。【结论】养肝活血中药治疗可改善多发性硬化合并周围神经病变症状及体征,是治疗多发性硬化合并周围神经病变的重要手段之一。
Objective To observe the therapeutic effect of therapy of nourishing liver and activating blood for the treatment of multiple sclerosis （MS） with peripheral neuropathy （PN）. Methods Twenty-six MS with PN patients admitted in out-patients department were enrolled into the study. The patients were given herbal medicine with the actions of nourishing liver and activating blood on the basis of routine western medicine. The relief of symptoms and signs of PN, score of nervous function evaluated by Expanded Disability Status Scale （EDSS） , eleetromyogram （EMG） were examined before treatment and one year after treatment. Results One year after treatment, symptoms and signs of PN were relieved, EDSS score was decreased, the latency of motor nerve and sensory nerve was shortened and conduction velocity was increased, and incidence of wave F was increased and its latency was shortened （P 〈 0.05 or P 〈 0. 01 ）. Conclusion Therapy of nourishing liver and activating blood can relieve the symptoms and signs of MS with PN, and is a feasible treatment option for MS with PN.
出处
《广州中医药大学学报》
CAS
2009年第6期529-531,582,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
多发性硬化/中药疗法
周围神经系统疾病/中药疗法
天麻首乌养肝活血汤/治疗应用
MULTIPLE SCLEROSIS/TCD therapy
PERIPHERAL NERVOUS SYSTEM DISEASE/TCD therapy TIANMA SHOUWU YANGGAN HUOXUE DECOCTION/therapeutic use
YANGGAN JIANPI YISUI HUOXUE DECOCTION/therapeutic use
