摘要
报告５例脊髓型多发性硬化（ＭＳ），其临床表现为脊髓损害的症状和体征，病程中均有缓解与复发。其中１例做了全身尸检，为国内首例尸检报告。病理特点：①脊髓白质广泛脱髓鞘改变；②枕叶白质有两处陈旧性软化灶而无临床症状与体征；③伴有周围神经脱髓鞘病变，并且周围神经病变与临床表现及电生理学检查相符。作者结合文献对ＭＳ的诊断。
Fivecasesofspinalcordmultiplesclerosisshowingonlyspinalsymptomatologythroughoutthecoursesofthediseasewerereported.Alofthesecasesdevelopedwithremissionsandrelapsesfor2to4times.Onecasewasverifiedwithautopsy.Toourknowledge,thisisthefirstpathomorphologicevidenceofthespinalformofMSinChina.Thepathologicalcharacteristicsinclud-edthefolowing:1)Therewaswidespreaddemyelinationinthewhitematerofthespinalcord.2)Thereweretwosmalremotemalaciclesionsinthewhitemateroftheoccipitallobesbutwithoutmanifectationofclinicalsymptomandsign.3)Therewasdemyelinationintheperipheralnerves.Thelesionsintheperipheralnerveshadalsobeenascertainedbyclinicalpathologicandelectrophysi-ologicevidences.
出处
《中华神经科杂志》
CAS
CSCD
1996年第1期19-22,共4页
Chinese Journal of Neurology
关键词
多发性硬化
脊髓型
诊断
病理
SpinalcordmultiplesclerosisDemyelination
