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丙型肝炎病毒感染与脂肪性肝病 被引量:5

HCV infection and liver steatosis
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摘要 HCV除引起肝脏损害外,还与肝细胞癌(HCC)以及某些肝外组织的损害表现密切相关。大量研究报道,HCV慢性感染与2型糖尿病、脂肪肝等代谢性疾病的发生、发展密切相关。肝脏脂肪变性是慢性丙型肝炎(chronic hepatitis C,CHC)的发病机制之一,CHC合并脂肪肝和糖尿病有着极高的发病率,提示CHC也是。种代谢性疾病。HCV与代谢综合征(metabolism syndrome,MS)密切相关,肝脏脂肪变性及胰岛素抵抗可能是HCV引发MS的中心环节,其分子生物学机制是病毒导致脂代谢紊乱。
作者 成军 张锦前
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2009年第11期804-806,共3页 Chinese Journal of Hepatology
关键词 肝炎病毒 丙型 肝疾病 脂肪肝 代谢综合征 Hepatitis C virus Liver diseases Fatty liver Metabolic syndrome
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