摘要
乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)及人类免疫缺陷病毒(HIV)具有相似的传播途径,均可通过血液、性接触及母婴传播。因此,在HIV感染者中常合并HBV、HCV感染。这为人们预防和治疗HIV/人类获得性免疫缺陷综合征(AIDS)合并HBV、HCV感染带来了巨大的挑战。随着高效抗逆转录病毒治疗(HAART)的广泛应用,肝脏相关性疾病已成为HIV感染者主要的合并症和死亡原因。本文就目前HIV/AIDS合并HBV、HCV感染的流行病学、相互影响、治疗等方面进行综述。
Human immunodeficiency virus （HIV） coinfection and/or superinfection with hepatitis B virus （HBV） and hepatitis C virus （HCV） are very common because of their shared ways of viral transmission. They are mainly spread through expo- sure to contaminated blood or blood products, sexual contact and mother - to - child transmission. It poses a huge challenge for prevention and treatment of the HIV/AIDS coinfection and/or superinfection with HBV and/or HCV. With the extensive applica-tion of highly active antiretroviral therapy （ HAART）, liver - related disease has become the main complication and causes of death in HIV/AIDS patients. This review will give a detailed introduction of the epidemiology of HIV/AIDS coinfection and/or su- perinfection with HBV and/or HCV, as well as characteristics of each virus and their interaction and strategies for treatment.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第9期955-958,共4页
Chinese General Practice
基金
国际合作项目--中国盖茨艾滋病项目(2010-11-G)
