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Kupffer细胞抑制剂氯化钆的研究现状 被引量:2

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摘要 氯化钆通过抑制Kupffer细胞,可缓解肝脏疾病的发生发展。这种作用表现在多个方面:氯化钆作用于Kupffer细胞,抑制吞噬和抗原提呈,进而抑制大鼠肝移植的急性排斥反应;缺血再灌注时,保护受伤的肝脏,促进肝细胞的再生;减轻对内毒素的敏感性及内毒素所致的感染作用;有效预防和减轻酒精性肝损伤等。该文对目前氯化钆抑制Kupffer细胞,进而减轻肝脏疾病的机制的研究现状综述如下。
作者 廖锐 龚建平
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2009年第10期791-794,共4页 Chinese Journal of Hepatobiliary Surgery
基金 国家自然科学基金资助项目(30471696,30500473)
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