摘要
目的 探讨影响胚胎冷冻结果及冻融胚胎移植后妊娠结局的因素。方法 用常规IVF -ET方法对 2 2例患者进行 2 4个周期的冻融胚胎移植 ,并对结果进行统计学分析。结果 2 2例患者 2 4个周期中平均每周期冷冻胚胎 5个 ,解冻后 ,每周期平均存活 4个 ,继续卵裂 3个 ,平均存活率为 83 3% ,继续卵裂率为 84 %。冷冻前、解冻后、移植胚胎 3组的胚胎平均评分分别为 8 2 ,8,7 5 ,组间无统计学差异 (P >0 0 5 ) ;移植后临床妊娠率达 2 2 7% ,每个取卵周期的临床妊娠率由 2 8 9%提高至 31 7% ;患者年龄、胚胎质量、子宫内膜状态与胚胎着床率密切相关。结论 :胚胎冷冻技术是对人类辅助生殖技术体系的重要补充和完善 ,成功的关键在于胚胎质量、适宜的冷冻程序。
Objective To investigate the factors affecting the results of embryo cryopreservation and the pregnancy results of embryo transfer following thawing.Method 22cases received embryo transfer following thawing in 24cycles under routine IVF-ET procedure.Results There were 4 embryo survived and 3 continously cleaved out of 5 frozen ones following thawing per cycles.The average surviving rate was 83.3% and continue cleaving rate was 84%.The average embryo score before cryopreservation,after thawing and tranfered was 8.2,8.0,7.5,respectively.No statistics differences of embryo score were found among the three groups(P>0 05).The pregnancy rate after transfer arrived at 22.7%,and the clinical pregnancy rate per oocyte retrieval cycle increased from 28.9% to 31.7%.In this study,the embryo implantation rate was closely related with age of patient,embryo quality,and condition of endometrium.Conclusion The technology of embryo cryopreservation is an important supplement for human assisted reproduction technique.The successful pregnancy rate of embryo cryopreservation depends on embryo qualilty,adoptive freeze procedure,endocrine environment and the synchronism between endometrium and embryo development.
出处
《云南医药》
CAS
2001年第6期437-439,共3页
Medicine and Pharmacy of Yunnan
基金
云南省"九五"攻关项目资助课题
关键词
胚胎冷冻
胚胎质量
胚胎移植
妊娠率
Embryo cryopreservation
Embryo transfer
Pregnancy rate.
