摘要
目的检测K i67在涎腺良、恶性肿瘤组织中的表达,研究其与涎腺肿瘤发生发展的临床病理意义。方法采用SP免疫组化染色方法检测38例涎腺肿瘤中K i67表达情况,采用SPSS软件统计分析。结果在正常涎腺组织中K i67蛋白呈阴性表达,在涎腺多形性腺瘤与涎腺恶性肿瘤中表达率分别为33.3%和75%,差别具有统计学意义。结论K i67蛋白的表达与涎腺肿瘤的发生、发展相关,其检测可辅助诊断涎腺肿瘤的良恶性。
Objective To examine the expression of Ki67 in benign or malignant salivary tumors and explore the relationship between the expression of Ki67 and the biological of the salivary rumors. Methods The expression of Ki67 in 38 salivary tumors patients are detected by immunohistochemistry. The data is analyzed by SPSS software. Results The expression of Ki67 in salivary are negative and the ratio of the expression of Ki67 in benign and malignant salivary tumors are 33. 5% and 75% respectively （P〈 0. 05）. Conclusion The expression of Ki67 is related with appearance and development of salivary tumors. A salivary tumors can be diagnosed to be benign or malignant by the detection of Ki67.
出处
《佛山科学技术学院学报（自然科学版）》
CAS
2009年第5期86-88,共3页
Journal of Foshan University(Natural Science Edition)
基金
佛山市科技攻关资助项目(200508088)
