摘要
胃癌是我国最常见的恶性肿瘤之一。对于进展期胃癌,传统手术和术后化疗的临床疗效并不理想。近年来,人们主张对进展期胃癌进行以手术为主的综合治疗。术前新辅助化疗为胃癌综合治疗方法之一,其作用日益受到肯定。新辅助化疗可减低肿瘤负荷,降低临床分期,提高手术切除率。本文对进展期胃癌新辅助化疗的基本理论、临床应用和化疗药物的选择作一综述。
Gastric cancer is one of the most commonly seen malignancies in China. The clinical efficacy of conventional surgical operation and postoperative chemotherapy is not satisfactory for patients with advanced gastric cancer. In recent years, comprehensive treatment is advocated, among which, the importance of preoperative neoadjuvant chemotherapy has been increasingly emphasized. Neoadjuvant chemotherapy can decrease tumor burden, lower clinical stage and increase the rate of surgical excision. In this article, the basic theory, clinical application and selection of chemotherapeutic drugs for neoadjuvant chemotherapy in advanced gastric cancer were reviewed.
出处
《胃肠病学》
2009年第9期561-564,共4页
Chinese Journal of Gastroenterology
关键词
进展期胃癌
新辅助化疗
治疗结果
肿瘤分期
存活率
Advanced Gastric Cancer
Neoadjuvant Chemotherapy
Treatment Outcome
Neoplasm Staging
Survival Rate
